Human trophectoderm cells are not yet committed

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چکیده

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Human trophectoderm cells are not yet committed.

STUDY QUESTION Are human trophectoderm (TE) cells committed or still able to develop into inner cell mass (ICM) cells? SUMMARY ANSWER Human full blastocyst TE cells still have the capacity to develop into ICM cells expressing the pluripotency marker NANOG, thus they are not yet committed. WHAT IS KNOWN ALREADY Human Day 5 full blastocyst TE cells express the pluripotency markers POU5F1, SOX...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2012

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/des432